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HUTCHMED Begins Global Phase Ia HMPL-A830 Trial
x/gsk
— Sep 28, 2026
HUTCHMED has begun the Phase Ia portion of a global first-in-human trial of HMPL-A830 in patients with advanced or metastatic solid tumors, with the first dose given in China on September 24. The antibody-targeted therapy is designed to deliver a KRAS inhibitor to EGFR-expressing tumors while blocking both KRAS and EGFR signaling; the early-stage study will assess safety, dosing and preliminary anti-tumor activity.
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Chris Dalton
Starting the first dose in China is practical but the global part will show if it works across populations.
Boil Advisories Lifted and Issued in Several Communities
Environment
— Sep 11, 2026
Boil-water advisories were issued in multiple communities after water-line breaks or leaks and have been lifted in several areas following repairs and satisfactory water tests, though a few locations still operate under advisories or emergency directives. The affected communities include Great Bend (KS), Modeste (LA), the Richmond County area, White Plains (KY), and Cedar Rapids (IA), with precise closures, testing, and lifting timelines noted for each locality.
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Gangwar Appointed Education Secretary as NEET Row Broadens Reshuffle
x/national-eligibility-cum-entrance-test-undergraduate
— Jul 23, 2026
The Appointments Committee of the Cabinet appointed Naresh Pal Gangwar, a 1994-batch IAS officer, as the new Secretary of the Department of Higher Education, with Vineet Joshi reassigned to the Ministry of Panchayati Raj amid protests over NEET paper leaks and exam irregularities. The reshuffle also spans other secretary-level postings across the government as scrutiny of the education sector continues.
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More Than 200 Republican Push to Repeal Inheritance Tax
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— Feb 13, 2025
Republican lawmakers are working to nix the federal inheritance tax, otherwise known as the “death tax.” According to Fox News , U.S. Rep. Randy Feenstra (R-IA.) is leading the effort and has the support of more than…
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IJR
FBI Nabs Saudi National Accused Of Hiding Bug In Toilet Paper To Spy On AI Giant’s Inner Sanctum
Dylan Kresak · 3 min · 56m
Wrong Numbers Posted by Iowa Lottery; Winners Who Already Cashed In Allowed to Keep Their Prize
Reporting
— Dec 1, 2023
Some lucky winners are finding their lottery prizes beat even crazier odds than usual after the Iowa lottery posted the wrong numbers. According to the IA Lottery Blog , a “human error” delayed Monday’s results and led…
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AP Top 25 College Football Teams
Ranking
College football fans argue endlessly over which programs deserve the top spots in the AP Poll based on wins, schedule strength, and legacy.
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