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Study Links Appendectomy to 58% Lower Colorectal Cancer Risk
x/colorectal-cancer
— Oct 2, 2026
A study of more than 30,000 patients found appendectomy for acute appendicitis was associated with a 58% lower relative risk of later colorectal cancer than antibiotic treatment alone. Researchers cautioned that the findings do not prove surgery prevents cancer and should not displace antibiotics as an option; further research is needed.
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Nicole Hardy
Doctors should keep looking into why this link shows up instead of rushing to operate on everyone.
Doctors Highlight Diet, Stress Links to Gut Health
Health
— 5d
Gut health is linked to more than digestion: the gut microbiome may affect muscle function, while chronic stress can disrupt digestion and bowel habits. Articles also highlight practical steps—including eating more fiber and diverse plant foods, considering fermented foods, managing stress, and limiting ultra-processed foods, which studies associate with higher colorectal cancer risk.
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Stephen Garcia Has No Evidence of Disease After Cancer Surgery
x/stephen-garcia
— Sep 23, 2026
Former South Carolina quarterback Stephen Garcia’s surgery achieved a complete resection, leaving no evidence of disease, though his stage IV colorectal cancer will require ongoing monitoring. David Pollack said his wife was doing well after a third brain-cancer surgery, while actress Magda Szubanski described her mantle cell lymphoma as an incurable relapse.
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Sam Okafor
David Pollack's wife going through multiple brain surgeries shows how hard cancer can be on families.
‘Dawson’s Creek’ Star Dead After Cancer Battle
x/james-van-der-beek
— Feb 11, 2026
Actor James Van Der Beek died Wednesday after a battle with colorectal cancer, his wife posted on social media. Van Der Beek became a heartthrob by starring in the film “Varsity Blues” and the teenage coming-of-age…
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IJR
America’s Electric Grid Could Throw Wrench In Big Tech’s AI Dreams
Dylan Kresak · 5 min · 1h
FDA Extends Exelixis Drug Review to March 2027
x/exelixis
— Sep 11, 2026
The FDA has extended Exelixis' NDA review for zanzalintinib in combination with atezolizumab/Tecentriq for metastatic colorectal cancer by three months, moving the action date to March 3, 2027 after updated safety and efficacy data were deemed a major amendment. The development of zanzalintinib as a next-generation cancer therapy continues, with the delay potentially impacting timelines for patients, investors, and partners awaiting a decision.
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Nicole Hardy
The FDA's move to examine the new safety data more closely makes sense, though it will likely delay any benefits for those counting on the combination therapy.
AP Top 25 College Football Teams
Ranking
College football fans argue endlessly over which programs deserve the top spots in the AP Poll based on wins, schedule strength, and legacy.
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BioNTech halts Phase 2 cancer vaccine trial
Health
— Aug 28, 2026
BioNTech and Genentech/Roche have terminated the Phase 2 trial of autogene cevumeran for ctDNA-positive, surgically resected high-risk colorectal cancer after an independent DSMB cited a numerical survival imbalance, with further continuation deemed unlikely to change outcomes. The company will analyze the data to refine patient selection, and a separate Phase 2 trial in pancreatic cancer remains ongoing.
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Heartfelt Final Message: James Van Der Beek Honored Family Before His Death
x/the-new-york-post
— Feb 11, 2026
In the final weeks of his life, James Van Der Beek turned his attention to family. The actor, best known for his role on “Dawson’s Creek,” died Wednesday after battling colorectal cancer, according to Page Six . His…
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‘Dawson’s Creek’ Actor James Van Der Beek Dies at 48
x/james-van-der-beek
— Feb 11, 2026
James Van Der Beek, the actor known best for “Dawson’s Creek” and “Varsity Blues,” has died of colorectal cancer. He was 48. Van Der Beek’s death was announced with a post on his Instagram page Wednesday, Feb. 11, per…
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‘Dancing With The Stars’ Alum Shares Final Laugh With James Van Der Beek as Friends Mourn TV Star
x/james-van-der-beek
— Feb 13, 2026
Alfonso Ribeiro is remembering the final hours he spent with James Van Der Beek, sharing an intimate bedside photo taken shortly before the actor’s death after a nearly three-year battle with colorectal cancer…
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Books
Attachment styles, not chemistry, run the chase-and-withdraw trap
Attachment strategies—not chemistry or character—drive the chase-and-withdraw pattern that keeps couples stuck.
11m · 2 reads
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GSK pays Hutchmed $110M upfront in deal worth up to $1.3B
x/gsk
— Sep 3, 2026
GSK agreed to license Hutchmed’s HMPL-A830, a KRAS-EGFR antibody-drug conjugate, for up to $1.295 billion including $110 million upfront, with global rights outside Mainland China, Hong Kong, Macau and Taiwan while Hutchmed retains development and commercialization duties in those regions. The collaboration targets initial trials in colorectal, pancreatic, and lung cancers, leveraging a dual KRAS-EGFR mechanism to improve efficacy and tolerability.
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Jared Kim
Dual-targeting KRAS-EGFR is an interesting bet, hope it actually improves tolerability and not just adds complexity.