disease.
abnormal biological process in an organism driven by a specific pathophysiological mechanism
LB Pharmaceuticals accelerates Phase 3 NOVA-2 timeline across 25 U.S. sites, targets 1H 2027 topline
LB Pharmaceuticals now expects topline results from the Phase 3 NOVA-2 trial of LB-102 in schizophrenia in the first half of 2027, ahead of prior guidance, with a planned pre-NDA FDA meeting in the second half of 2027. The company highlights faster enrollment across about 460 patients at 25 U.S. sites, possible open-label extension and ongoing Phase 2 studies in bipolar depression and major depressive disorder, plus a cash runway into 2029 to support multiple readouts.
Business · 6 sources · Jul 22, 2026Read itThe journal
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About disease
A disease is a particular abnormal condition that adversely affects the structure or function of all or part of an organism and is not immediately due to any external injury. Diseases are often known to be medical conditions that are associated with specific signs and symptoms. A disease may be caused by external factors such as pathogens or by internal dysfunctions. For example, internal dysfunctions of the immune system can produce a variety of different diseases, including various forms of immunodeficiency, hypersensitivity, allergies, and autoimmune disorders.
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