2010–present: Career expansion
In 2010, he and wife Amy Madigan appeared together in Ash Adams' independent crime drama Once Fallen. Later that same year Harris starred in the survival drama The Way Back as Mr. Smith. His performance received much critical praise, and he was suggested by critics to receive a fifth Oscar nomination. Also in 2010, he portrayed the role of Jason Hudson in Call of Duty: Black Ops. In 2012, he co-starred alongside Sam Worthington in the thriller film Man on a Ledge for Summit Entertainment. He then won the Golden Globe Award for Best Supporting Actor – Series, Miniseries or Television Film and was nominated for the Primetime Emmy Award for Outstanding Supporting Actor in a Limited or Anthology Series or Movie for his performance as Senator John McCain in the HBO made for television drama Game Change.
In 2013, Harris reunited with director Michael Bay in the true crime film Pain & Gain, appeared in the post-apocalyptic thriller Snowpiercer, the western thriller Sweetwater, and starred opposite Annette Bening in the romantic drama film The Face of Love. Harris then voiced Mission Control in Alfonso Cuarón's space epic Gravity (2013), starring Sandra Bullock and George Clooney. He also voiced Blade Ranger in the animated film Planes: Fire & Rescue (2014). In 2015, he portrayed the title character in the film version of the Shakespeare tragedy Cymbeline, and starred with Liam Neeson in the action thriller Run All Night. In 2016, he appeared alongside Madigan and Taissa Farmiga in The New Group's revival of Sam Shepard's Buried Child, for which he was nominated for the Lucille Lortel Award for Outstanding Lead Actor in a Play.
In 2016, he also began playing the villainous Man in Black in HBO's sci-fi thriller series Westworld, and had a co-starring role in the ensemble cast of Warren Beatty's romantic comedy drama Rules Don't Apply, with Lily Collins and Alden Ehrenreich. In 2017, he appeared in Dean Devlin's sci-fi film Geostorm, alongside Gerard Butler and Andy Garcia. Harris had been previously set to star in Alejandro González Iñárritu's Starz drama series The One Percent with Hilary Swank and Ed Helms. Harris co-starred in Darren Aronofsky's horror film Mother! (2017), alongside Jennifer Lawrence, Javier Bardem, Michelle Pfeiffer, and Domhnall Gleeson. Harris also starred in the 2017 movie Kodachrome. His performance was widely regarded as one of the film's highlights.
In 2019, Harris took over the role of Atticus Finch in Aaron Sorkin's stage adaptation of To Kill a Mockingbird on Broadway. The role was previously played by original cast member Jeff Daniels. In 2021, he starred in Maggie Gyllenhaal's psychological drama The Lost Daughter. In 2022, Harris played Rear Admiral Chester "Hammer" Cain in the blockbuster film Top Gun: Maverick. Harris was in the film Love Lies Bleeding as Lou Sr. in 2024. On May 13, 2024, Harris was set to direct and write the feature film adaptation of Kim Zupan's neo-noir crime thriller novel The Ploughman, starring Owen Teague, Nick Nolte, Bill Murray, Madigan and their daughter Lily Harris.