Voice acting
David also works extensively as a voice actor. He was the voice of the Flame King in Adventure Time, King Andrias from Amphibia, Goliath from Gargoyles, the title character in the Spawn animated series, and Lemuel Kane in Archer. In the English dub of Princess Mononoke, David played the narrator and Okkoto. He played the role of Mama in the English dub of 3×3 Eyes. He provided the voice for the character Decker in the role-playing video game Fallout and the voice for the character Vhailor in Planescape: Torment. He provided the voice of the Arbiter for the video game Halo 2, released in 2004; later, he reprised that role in the Xbox 360 follow-up Halo 3. He voiced the character again in Halo: The Master Chief Collection and also in Halo 5: Guardians, released in 2014 and 2015 respectively. He played the role of Captain David Anderson in BioWare's Mass Effect trilogy.
David did voice work in the video game Saints Row and its sequel Saints Row II, playing gang leader of the 3rd Street Saints Julius Little, as well as voicing himself in Saints Row IV.
He is also heard on the intro of several Ice Cube projects, including Westside Connection's 2003 release Terrorist Threats, Cube's 2008 solo album Raw Footage, Cube's 2010 solo album I Am the West, and he narrated the documentary Beef II, which also featured Ice Cube.
He provides the voice for the UPS "What Can Brown Do for You" commercials. He did the voice of Despero in the two part episode "Hearts and Minds" of Justice League. He has done voice work for early Adult Swim commercials for Inuyasha.
He has worked with documentary filmmaker Ken Burns numerous times, narrating Burns' Jazz, Mark Twain, The War, Unforgivable Blackness: The Rise and Fall of Jack Johnson, Jackie Robinson, Muhammad Ali, and Leonardo da Vinci. David won the Emmy Award for Outstanding Voice-Over Performance for his work in The War and Unforgivable Blackness. He performs the narration duties in the BBC documentary, World War II: Behind Closed Doors.
The 2004 PBS documentary Ancient Refuge in the Holy Land and the 2005 History Channel documentary Crusades: Crescent & the Cross focusing on the medieval Crusades were both narrated by him, as well as the 2003 National Geographic documentary Inside Mecca. He later parodied his documentary work by narrating the 2012 episode of Community, "Pillows and Blankets", a mockumentary revolving around a pillow fight between rival blanket forts.
David has done voice-over work for many other documentaries including several for National Geographic and the documentary Comic Book Superheroes Unmasked for the History Channel. He replaced Paul Winfield as narrator for the A&E show City Confidential, taking over after Winfield's death in 2004. He voiced the trailer for the film Primeval, which was released in the United States on January 12, 2007.
David provided the voice of police detective Alex Cross for the audiobook versions of three novels by James Patterson: Cat and Mouse (1997), Pop Goes the Weasel (1999), and Roses are Red (2000). Other voice roles include Bebe Proud Clone from The Proud Family Movie, Atlas from Teen Titans, the lone renegade male gorilla Tublat in The Legend of Tarzan, and the Decepticon Barricade in Transformers: The Game.
He voiced Apollo the Sun God in Hercules (1997), Council Member in Final Fantasy: The Spirits Within (2001), Chaos in Dissidia Final Fantasy (2008), the Black Cat in Coraline (2009), Sergeant Foley in Call of Duty: Modern Warfare 2 (2009), Dr. Facilier in The Princess and the Frog (2009), and Big Man in The Spectacular Spider-Man episode "Survival of the Fittest".
On May 25, 2008, he narrated Kansas City's Celebration at the Station, a Memorial Day service held annually at the World War I Memorial. During the ceremony, he announced the attendance of Frank W. Buckles, the last living veteran of World War I. He was the voice of Frederick Douglass in the third episode of the PBS documentary God in America: How Religious Liberty Shaped America in 2010.
David returned to the Saints Row series in Saints Row IV, voicing a fictionalized version of himself as well as reprising Julius Little. He is the narrator of the History Channel series The Bible which premiered on March 3, 2013.
David voiced the superhero gorilla Solovar in the two-part Gorilla City episode of The Flash. Keith David also has a recurring role as the President of the United States in the adult animated series Rick and Morty, a role that has been spun off as the lead character in its own President Curtis (2026) series.
David was the narrator of the MLB Network special Mr. Padre, the video biography of San Diego Padres Hall-of-Fame outfielder Tony Gwynn.
David has also narrated several WWE documentaries including The True Story of Wrestlemania and the 20 episodes of The Monday Night War, documenting the battle between WWE Raw and WCW Nitro.
David later recurred in Stargirl as the voice of Mister Bones.
David began voicing Commander Zavala in the Destiny franchise beginning in Destiny 2: The Final Shape, replacing Lance Reddick following his death in 2023.
David also voiced the character Brian Robertson in the revival series of King of the Hill.
In 2026, David starred in an audio drama retelling of Robert Louis Stevenson’s Treasure Island. The eight-hour production, written and directed by Orson Ossman, is titled "Treasure Island: A Telling for the New World."