Matsubara (written 松原) is a Japanese surname. Notable people with the surname include:
Arisa Matsubara (松原 有沙; born 1995), Japanese women's footballer
Hiroki Matsubara (松原 浩樹; born 1973), Japanese footballer
Hisako Matsubara (松原 久子; born 1935), Japanese writer
Jin Matsubara (松原 仁; born 1956), Japanese politician
Ken Matsubara (松原 健; born 1993), Japanese footballer
Kiyomatsu Matsubara (松原 喜代松; 1907–1968), Japanese marine biologist
Kozo Matsubara (松原 光三; born 1949), Japanese handball player
Masayuki Matsubara (松原 正之; born 1939), Japanese sport wrestler
Miki Matsubara (松原 みき; 1959–2004), Japanese singer-songwriter and composer
Matsubara Naoko (松原 直子; born 1937), Japanese artist
Osamu Matsubara (松原 治; died 2012), Japanese businessman
Rie Matsubara (松原 梨恵; born 1993), Japanese rhythmic gymnast
Takehisa Matsubara (松原 武久; born 1937), Japanese politician
Takeo Matsubara (松原 武生; 1921-2014), Japanese physicist
Tsuyoshi Matsubara (松原 剛志; born 1979), Japanese singer and actor
Yoshika Matsubara (松原 良香; born 1974), Japanese footballer
Yuki Matsubara (松原 優吉; born 1988), Japanese footballer