In Greek mythology, Opheltes (Ancient Greek: Ὀφέλτης, lit. 'helper' or 'benefactor') may refer to several figures in Greek mythology, including:
Opheltes, the infant son of Lycurgus of Nemea, killed by a serpent.
Opheltes, one of the Tyrrhenian pirates who attempted to deceive and kidnap Dionysus, and were changed by the god into fish or dolphins.
Opheltes, the son of Peneleos, who died in the Trojan War. He was the father of Damasichthon, a king of Thebes.
Opheltes, an experienced Trojan warrior. He was the father of Euryalus who accompanied Aeneas to Italy.
Opheltes, a Dolionian killed by Telamon in the battle between the Dolionians and the Argonauts.
Opheltes, son of Arestor, a soldier in the army of Dionysus during the Indian campaign, killed by Deriades.