Member of Parliament
In the 2024 general election on 4 July, Lowe stood for the Great Yarmouth constituency, and won, gaining 35.3 percent of the vote. After his election, he compiled a list of schools in his constituency where he said that teachers were biased against Reform during the election campaign, saying he would be meeting with headteachers to discuss the allegations. He has also pledged to donate his MP salary to a different local charity or worthy cause each month.
In January 2025, the American businessman Elon Musk, who had endorsed Reform UK, called on Nigel Farage to resign as leader, and then praised Lowe. Lowe thanked Musk, but reiterated his support for Farage. The dispute between Musk and Farage stemmed from Musk's endorsement of political activist Tommy Robinson, whom Farage has rejected; Lowe said Robinson should be acknowledged for "exposing these [child rape] gangs" but called him "not right for Reform".
On 8 January 2025, Lowe brought in a Ten Minute Rule Bill to ban quantitative easing, praising Argentinian president Javier Milei and looking forward to Musk working with American president Donald Trump, before saying "The cost of government should be covered by taxes alone, limiting the growth of excessive statism" which he said was linked to "a general moral decline in society". As of October 2025, it has not received a second reading. Also in January 2025, Lowe voted along with other Reform UK MPs to block the Children's Wellbeing and Schools Bill with a motion that called for a new national inquiry into the grooming gangs scandal. The amendment was defeated at 364 votes to 111, a majority of 253 against the amendment.
On 6 March 2025, in an interview with the Daily Mail, Lowe criticised the governance of Reform UK as "a protest party led by the Messiah", suggesting he might leave the party if things did not change, and saying it was too early to tell whether Farage would make a good prime minister. Farage disputed Lowe's criticism of himself and Reform UK, describing his personal following as a good thing, and went on to suggest Lowe's remarks were driven by a desire to be prime minister himself. In the same Daily Mail interview, Lowe stated he thought that MPs' pay should be increased to about £250,000 a year with the size of the House of Commons halved, and described the BBC as a "cancer at the heart of Britain".
In June 2026 he published The Rape Gang Inquiry Report, an unofficial crowd-funded report that alleged that at least 250,000 white girls were subjected to "repeated rape, gang rape, trafficking, torture, pregnancy, forced Islamic conversion and lifelong trauma", while acknowledging imprecision over the figure, stating this is because the numbers were not recorded. It also alleged that the police, social services, schools, the National Health Service, licensing authorities, and governments allowed the gangs to operate "with impunity", and that these crimes have been happening since the 1950s. The report does not support the 250,000 figure with original data, but draws on extant material, including advocacy material (such as that of the evangelical group Christian Concern), and has been criticised as inaccurate and misleading. The Police Service of Northern Ireland stated that "they can find no evidence that suggest any of the findings are true."