IJR News — today's news from every side

IJR News — today's news from every side

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Genius — OpenServe

NYC Deal Would Phase Out Horse-Drawn Carriages — 1dMamdani and Menin backed Romanch's Law to end NYC horse carriages by June 1, 2028, named for an 18-year-old tourist who died after a crash.

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Argenx FB102 meets Phase 2 celiac endpointHealth — 6dArgenx Phase 2 FB102 trial in 126 celiac adults met the primary endpoint (Vh:Cd p=0.0176); firm plans Phase 3. Same day it halted the Sjögren's UNITY study.

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Syndax Ends Axatilimab IPF Development After Trial MissHealth — 2dSyndax ends axatilimab IPF development after the 145-patient MAXPIRe Phase 2 missed its FVC endpoint; SNDX dropped overnight as BMS also released ALOFT-IPF results.

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TOP Financial establishes Houston headquarters, expands boardBusiness — 14hTOP Financial Group established its global headquarters in Houston as it shifts its principal executive office to the United States, with a phased relocation of executives while regional offices remain open. It also expanded its board from five to seven members, naming Jennifer Hoi Ling Tam co-CEO and adding Dean Huge and Yuli Yan; the company says the changes support its North American growth and governance strategy.

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Elena Vasquez Keeping regional offices open during the shift shows they're not rushing the move.

IJRTop Trump Dinner Bidders Stash Cash On Exchanges That Shut Out AmericansDylan Kresak · 3 min · 4h

Samaritan-MultiCare Merger Set to Close Nov. 1Health — 1dSamaritan Health Services will join Washington-based MultiCare Health System on Nov. 1 after clearing regulatory reviews. MultiCare has pledged $700 million over 10 years for Samaritan’s facilities, workforce and access to care; Samaritan will retain its name and local leadership, and officials say the phased integration will not disrupt patient care or coverage.

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AP Top 25 College Football TeamsRankingCollege football fans argue endlessly over which programs deserve the top spots in the AP Poll based on wins, schedule strength, and legacy.

Brisbane 2032 CEO Cindy Hook to step down after contract ends — 2dBrisbane 2032 Olympics organizing committee CEO Cindy Hook will leave when her contract ends in late 2026, as the Games move from planning into operational delivery. Organizers will begin an immediate search for her successor, with Hook and committee leaders saying she has laid the groundwork for the next phase.

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Kansas City plans two-year I-670 closure for parkTravel — 2dInterstate 670 in downtown Kansas City is scheduled to close in both directions from early December 2026 through September 2028 as crews build the first phase of Roy Blunt Luminary Park, an elevated green space intended to reconnect downtown and the Crossroads. The work includes roughly half of the highway tunnel and the park’s first block; nearby streets will also face intermittent closures, and the prolonged shutdown will overlap with an I-70 closure east of downtown.

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From Stockpile To Supply Chain: Project Vault’s Next Phase — 6dFor years, Washington has understood the strategic danger created by America’s dependence on foreign sources for critical minerals. These materials sit at the foundation of every t… — by Daily Caller News Foundation

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Accelsius Upgrades Austin Lab for Multi-Megawatt AI CoolingBusiness — 2dAccelsius upgraded its Austin lab to multi-megawatt capacity, enabling testing of its two-phase NeuCool liquid-cooling systems under warm-water conditions and at the high rack densities expected for next-generation AI data centers. The company plans to add 18,000 square feet in January 2027 and expand its product line with a 375-kilowatt-capable unit.

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BooksHow a broken blood test raised nine billion on pure storyAnyone funding or boarding a startup should see how a non-working finger-prick device rode charisma and legal threats to a nine-billion-dollar valuation.24m

FDA Approves Pfizer Tukysa Combo for Metastatic Breast Cancer MaintenanceBusiness — Oct 7, 2026FDA approved Pfizer's Tukysa combo as front-line maintenance for metastatic HER2-positive breast cancer on Oct. 7, 2026; a Phase 3 trial showed a 36% lower risk of progression or death.

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AbbVie’s Zumilokibart Hits EASI-75 Goal in Phase 2 Eczema Trial — Sep 30, 2026At EADV 2026, long-term ADlong results showed sustained efficacy and safety with lebrikizumab through week 108, with 92.9% of participants achieving EASI-75. Separately, AbbVie’s Phase 2 trial found all zumilokibart doses beat placebo on the week-16 EASI-75 endpoint, and the mid-dose regimen was selected for Phase 3 development.

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Most Influential Women in World HistoryYourlist — RankingFrom ancient queens who ruled empires to modern activists who changed laws, these women left indelible marks on politics, science, and culture. Vote for who you think shaped history most profoundly.

Solar Projects Break Ground in Arizona, Nevada — Oct 6, 2026SunPower has broken ground on the first phase of a solar power system for a new AI data center in Reno, Nevada. The company says the complex installation will help expand its capabilities in commercial projects with demanding performance requirements.

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TC Energy Advances Coastal GasLink Phase 2 Expansion After LNG Canada Decision — Sep 29, 2026

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San Antonio Approves SAWS Hikes Up to 29%Politics — 6dSan Antonio’s City Council approved phased SAWS rate increases for 2027–2030, potentially raising average residential bills by about $13–$17 a month by 2030 to fund system improvements. Councilwoman Misty Spears opposed the plan, citing transparency and affordability concerns, while Councilmember Ric Galvan supported it but called for measurable improvements and accountability.

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IJRPolitical Debanking Ran Rampant At America’s Biggest Banks, Federal Probe AllegesJack McGeever · 5 min · 6h

Vaxcyte to Present Topline Phase 3 Data for VAX-31 Vaccine — Oct 4, 2026VAX-31 met noninferiority on all 28 shared serotypes and superiority on 3 unique ones in Oct. 5 OPUS-1 data; Pickering called it a new class benchmark.

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Tom Gallagher Phase 3 data due October 5 should show whether this beats Prevnar 20 or not.

New York Pizza vs Chicago Deep DishYourlist — VS BattleThe foldable slice versus the fork-and-knife casserole — America's longest-running food fight.

Glaukos Reports Durable Three-Year Epioxa Trial ResultsHealth — Oct 7, 2026Glaukos reported three-year Phase 3 extension results for Epioxa, showing sustained corneal improvement and visual gains after one treatment, with no serious or treatment-related adverse events reported. Despite the positive data, one report said the company’s shares fell more than 13%, amid valuation concerns and insider selling.

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Brink’s Wins UK CMA Backing for Planned NCR Atleos DealBusiness — 6dThe U.K. Competition and Markets Authority has accepted in principle Brink’s proposal to sell NoteMachine/TestLink UK to address competition concerns over its planned acquisition of NCR Atleos, avoiding a Phase 2 review if the divestiture is completed. Brink’s says the deal remains on track to close in early 2027 and maintains its expectation of $200 million in annual cost synergies within three years of closing.

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Acadia Plans Phase 3 After Alzheimer’s Drug Endpoint Miss — Sep 24, 2026Acadia’s 60 mg remlifanserin cut Alzheimer’s psychosis scores 12.6 vs 10.4 for placebo but missed significance (p=0.0603); Phase 3 continues without the 30 mg arm.

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Sam Okafor A 2 point difference on the scale is modest at best, so phase 3 success is far from guaranteed.

Pennsylvania Senate Passes PFAS Foam Ban BillPolitics — Oct 5, 2026Pennsylvania’s Senate approved a bipartisan bill, 48-1, to phase out PFAS-containing firefighting foam, restricting its manufacture, sale and distribution beginning in July 2027 and its use starting in 2028. The measure also requires warning labels on protective gear containing PFAS, chemicals linked to health risks and environmental contamination; a companion bill passed the House unanimously in 2025.

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BooksWhy structure beats intention in every stubborn system failureAnyone stuck in policy resistance or a tragedy of the commons will see why Meadows says stocks, loops, and high leverage points—not better people—drive the pattern.28m

Texans’ Ryans Considers Taking Over Play-CallingSports — Oct 4, 2026After Houston’s 0-4 start, coach DeMeco Ryans said he was not making immediate staff or personnel changes, but left open the possibility of taking defensive play-calling duties from Matt Burke. Following a 34-30 loss to Dallas, Ryans faulted defensive breakdowns and penalties and said the team must improve across all phases.

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Louisville Opens First Outdoor Roller Rink at Lannan ParkSports — Oct 6, 2026Kelowna is revising plans for a delayed five-court indoor tennis facility after ending its partnership with Tennis Clubs of Canada, while a Tipperary club has applied to add two courts to meet demand. Ephrata has opened six pickleball courts as the first phase of a larger recreation hub, and Louisville has converted underused tennis courts at Lannan Park into its first designated outdoor roller-skating rink.

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J&J's Caplyta meets main goal in bipolar mania phase 3 trial — Sep 21, 2026J&J’s Caplyta cut manic symptoms 4.8 YMRS points more than placebo at Week 3 in Phase 3 Study 451; not yet approved for bipolar mania.

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Marcus Bell This success in the phase 3 trial gives real hope for new bipolar mania options that actually work.

GE HealthCare Plans $945 Million SOFIE Acquisition — Oct 5, 2026GE HealthCare agreed to acquire SOFIE Biosciences for $945 million in cash, expanding its U.S. PET radiopharmaceutical manufacturing and distribution network and strengthening its position in the growing precision-imaging market. The deal, expected to close in the first half of 2027 pending regulatory approval, also gives GE HealthCare U.S. rights to the Phase III imaging agent FAPI-74.

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Rural Medical Drone Tests Planned in Michigan, TaiwanTech — Oct 5, 2026A northern Michigan medical-drone pilot is entering its second phase, with FAA-approved test flights between Munson facilities scheduled for Oct. 6–30 to simulate deliveries of medical supplies, lab samples and medications. The expanded tests will use longer routes, multiple drones and sensor technology to assess whether drone logistics can speed care and serve rural communities.

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IJROver 20 State Treasurers Warn Agencies Against Using ESG For Deciding Credit RatingsJack McGeever · 4 min · 6h